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Pregnancy loss 9X more likely if male had less than 20 ng of Vitamin D – July 2021

Male vitamin D status and male factor infertility

Fertil Steril. 2021 Jul 18;S0015-0282(21)00535-5. doi: 10.1016/j.fertnstert.2021.06.035 $36 0aywall
Nicole Banks 1, Fangbai Sun 2, Stephen A Krawetz 3, R Matthew Coward 4, Puneet Masson 5, James F Smith 6, J C Trussell 7, Nanette Santoro 8, Heping Zhang 2, Anne Z Steiner 9

Vitamin D Life

Fertility and Sperm category contains the following summary

134 items in Fertility or Sperm in Vitamin D Life

See also:
Overview Women and Vitamin D
Overview Pregnancy and vitamin D    Fertility and Vitamin D – several articles
Endometriosis
Ensure a healthy pregnancy and baby - take Vitamin D before conception
IVF OR "IN VITRO FERTILIZATION" etc. in 18 Vitamin D Life titles


Vitamin D greatly improves Fertility

Increased male Vitamin D increases fertility

Decreased Fertility if decreased Vitamin D Receptor


  • "After accounting for abortion availability and the characteristics of pregnant women, the rate of reported miscarriages increased by about 1.0% per year. "

Image
 Download the PDF from Vitamin D Life
Speculation by Vitamin D Life: Might the increased miscarriage rate be associated with decreased Vitamin D levels?


Apparently: Pregnancy loss =miscarriage = spontaneous abortion (up to 20 weeks gestation)

Vitamin D Life pages containing PREGNANCY LOSS or MISCARRIAGE in title

Items found: 38
Title Modified
Miscarriage and low Vitamin D – many studies 03 Apr, 2024
Miscarriage (Recurrent Spontaneous) associated with poor CYP27B1 gene - Jan 2024 01 Feb, 2024
Recurrent miscarriages decreased by increased Vitamin D levels - Jan 2024 29 Jan, 2024
Miscarriage 2.5X more likely if second-hand smoke and low vitamin D – Sept 2022 06 Sep, 2022
Miscarriage 1.6 X more likely if low vitamin D – meta-analysis May 2022 09 Jun, 2022
Recurrent Miscarriage 4X more likely if low vitamin D – meta-analysis June 2022 07 Jun, 2022
Recurrent pregnancy loss (miscarriage) risk should be reduced by vitamin D, vitamin B12 – March 2021 24 Dec, 2021
Researchers found flu vaccine increased miscarriage risk by 7X -Sept 2017 24 Dec, 2021
Recurrent miscarriage associated with low Vitamin D – Nov 2013 24 Dec, 2021
Pregnancy loss 9X more likely if male had less than 20 ng of Vitamin D – July 2021 22 Jul, 2021
Recurrent pregnancy loss (miscarriage) is associated with low vitamin D in 6 ways – March 2021 25 Mar, 2021
Recurrent miscarriage occurs 2.2 more often if poor Vitamin D Receptor – Aug 2019 26 Feb, 2021
Higher risk of Recurrent Pregnancy Loss if poor Vitamin D Receptor – Feb 2021 07 Dec, 2020
Spontaneous Miscarriage strongly associated with 2 vitamin D genes – March 2020 15 Feb, 2020
Preterm birth 9 X more likely if fetus had a poor Vitamin D Receptor and previous miscarriage – Aug 2017 12 Nov, 2019
Miscarriage 32 percent more likely if work night shift (probably low Vitamin D) – April 2019 05 Apr, 2019
Miscarriage 2 times more likely if low vitamin D – meta-analysis May 2017 05 Apr, 2019
Recurrent pregnancy loss – Low Vitamin D is a suspected risk factor – Sept 2018 24 Sep, 2018
Miscarriage 10 percent more likely for each 10 ng less vitamin D at preconception – May 2018 01 Aug, 2018
Miscarriages strongly associated with poor placental, decidua gene which locally activates Vitamin D – Dec 2016 28 Jul, 2018
Second miscarriage associated with low vitamin D – review June 2018 20 Jun, 2018
Pregnancies with more than 40 ng of vitamin D are great - miscarriage, LBW, SGA, preterm – Feb 2018 14 Feb, 2018
Pregnancies with more than 40 ng of vitamin D are great - miscarriage, LBW, SGA, preterm – Feb 2018 14 Feb, 2018
Cesarean (associated with low Vitamin D) increased asthma, obesity, miscarriage and stillbirth – meta-analysis Jan 2018 26 Jan, 2018
Early menarche, miscarriage and stillbirth are associated with heart disease (all are associated with low Vitamin D) – Jan 2018 18 Jan, 2018
Bone loss during black pregnancies – 4000 IU of vitamin D was not enough – Dec 2017 12 Dec, 2017
Preterm birth far more likely if previous miscarriage and poor Vitamin D receptor – Aug 2017 20 Nov, 2017
APS (associated with miscarriage, stillbirth. preterm delivery and stroke) is 3X more likely if low vitamin D – meta-analysis Oct 2017 13 Oct, 2017
Frequent miscarriage associated with both lower vitamin D and poor Vitamin D receptor – Sept 2017 14 Sep, 2017
Miscarriage in first trimester 2.5X more likely if less than 20 ng of vitamin D – July 2015 07 Jul, 2017
Miscarriage 70 percent more likely if low vitamin D (see also data on CYP27B1) – May 2016 07 Jul, 2017
Just 400 IU of daily Vitamin D reduced miscarriage (recurrent) by 3.5 times – RCT July 2016 07 Jul, 2017
Preterm birth 2X more likely if poor Vitamin D Receptor, 9 X if also had previous miscarriage – June 2017 15 Jun, 2017
Infants have low levels of vitamin D – associations with phototherapy and miscarriage – Dec 2016 01 Jan, 2017
Infants have low vitamin D levels in infants – association with phototherapy and miscarriage – Dec 2016 01 Jan, 2017
Recurrent miscarriage associated with half as much vitamin D getting to fetus – Sept 2016 07 Aug, 2016
Miscarriage 3X more often if very low vitamin D – Jan 2016 12 Jun, 2016
Miscarriage in 2nd trimester associated with low vitamin D – July 2012 07 Sep, 2015

Why all companies should offer leave for pregnancy loss Fast Company July 2021

  • "A 2020 study found that one in six women who have a miscarriage or an ectopic pregnancy suffer from long-term post-traumatic stress. When you consider that anywhere from 10-20% of known pregnancies end in miscarriage, that’s a lot of people who likely end up suffering privately at work, unable to take time off to recuperate."


Objective: To determine the association between vitamin D levels in the male partner and fertility outcomes in couples with mild male factor infertility.

Design: Secondary analysis of a randomized, controlled trial.

Setting: Nine fertility centers in the United States.

Patient(s): Men (n = 154) with sperm concentration between 5 and 15 million/mL, motility ≤40%, or normal morphology ≤4% were eligible. Female partners were ovulatory, ≤40 years old, and had documented tubal patency.

Intervention(s): Men provided semen and blood at baseline for semen analysis and 25-hydroxyvitamin D (25(OH)D) levels. They were randomly assigned to receive a vitamin formulation including vitamin D 2,000 IU daily or placebo for up to 6 months. Couples attempted to conceive naturally during the first 3 months and with clomiphene citrate with intrauterine insemination of the female partner in months 4 through 6.

Main outcome measure(s): Primary: sperm concentration, motility, morphology, and DNA fragmentation at baseline. Secondary: cumulative pregnancy, miscarriage, and live birth rates.

Result(s): Semen parameters and sperm DNA fragmentation were not statistically significantly different between men with vitamin D deficiency and men with 25(OH)D levels ≥20 ng/mL. In addition, clinical pregnancy and live birth rates were similar. Male 25(OH)D level <20 ng/mL was associated with a higher rate of pregnancy loss (adjusted odds ratio 9.0; 95% confidence interval 1.3 to 61.3).

Conclusion(s): Vitamin D deficiency in the male partner did not significantly impact semen parameters or treatment outcomes. Further study is warranted to better characterize the rate of miscarriage in couples with male vitamin D deficiency.


Created by admin. Last Modification: Friday July 23, 2021 12:46:54 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
15960 pregnancy loss trend.jpg admin 23 Jul, 2021 38.23 Kb 283
15959 Spontaneous Abortions - 1970–2000.pdf admin 23 Jul, 2021 423.71 Kb 224